An enzymatic preparation from human brain converts tryptamine to tryptoline (9H-1,2,3,4-tetrahydropyrido[3,4-b]indole) in the presence of 5-methyltetrahydrofolic acid. Similarly, N-methyltryptamine and 5-hydroxytryptamine yield 1-methyltryptoline and 5-hydroxytryptoline, respectively. Neither in vitro nor in vivo formation of these compounds by human tissues has been described.
No takes yet. Share an insight, caveat, or question.
Wyatt et al. (1975) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: