Molecularly Imprinted Polymers with Strong Carboxypeptidase A‐Like Activity: Combination of an Amidinium Function with a Zinc‐Ion Binding Site in Transition‐State Imprinted Cavities

Impressing models: A novel polymer catalyst shows even higher catalytic activity for the hydrolysis of carbonates than catalytic antibodies prepared for the same purpose. The catalyst was prepared by molecular imprinting with a stable transition state analogue and the introduction of an amidinium function and a Zn2+ ion in the active site in a defined orientation (see picture).