Key result
Adding risperidone to an SSRI is linked to improved chronic depression.
Why the study?
Does adding risperidone to a selective serotonin reuptake inhibitor improve chronic depression?
Does adding risperidone to a selective serotonin reuptake inhibitor improve chronic depression?
Adding risperidone to SSRI therapy may offer clinical improvement for patients with chronic depression.
Should not yet guide SSRI augmentation; leaves open adjunctive risperidone role pending higher-level evidence.
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O’Connor et al. (1998) studied this question. Adding risperidone to a selective serotonin reuptake inhibitor improves chronic depression.
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