A new cocrystal of Vitamin D 3 (Cholecalciferol) and resorcinol has been discovered and characterized through experimental cocrystal screening. Its high stability has been studied against light, heat, and chemicals present in animal food premixes in order to develop a novel and alternative formulation to current microencapsulation approaches to protect Vitamin D 3 from oxidation. Our results show that the new cocrystal is extremely stable and it can become the basis for very efficient formulations of Vitamin D 3 which fulfills the stability requirements of industrial applications.
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Bofill et al. (2021) studied this question.
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