Key result
Radical resection and adjuvant treatment achieve complete 5-year disease control in pediatric lumbar intraneural synovial sarcoma.
Why the study?
Primitive intraneural synovial sarcomas are rare in children and have not been previously described in the lumbar nerve root location in this age group.
Case Report (n=1)
Early diagnosis and a multidisciplinary approach are essential for managing rare pediatric intraneural synovial sarcomas of the spinal nerve roots.
May support multimodal therapy in rare pediatric intraneural sarcoma; leaves open need for larger series before practice change.
Primitive intraneural synovial sarcomas are rare in children. The authors report the case of a 7-year-old girl affected by intraneural synovial sarcoma of a lumbar nerve root, the first such lesion in this location described in a child. The lesion mimicked a schwannoma clinically and radiologically. There was long-lasting leg pain in a radicular distribution, and a well-demarcated intraneural tumor was seen on MRI. On this basis, the first resection was conservative. However, histological examination documented a classic biphasic synovial sarcoma, which was confirmed by immunohistochemistry. After radical resection and adjuvant treatment, complete disease control was achieved and verified at 5-year follow-up. This case strongly suggests that early diagnosis and a multidisciplinary approach to this unusual spinal lesion are essential to achieving a better prognosis.
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Peia et al. (2013) conducted a case report in Intraneural synovial sarcoma of a lumbar nerve root (n=1). Radical resection and adjuvant treatment was evaluated on Complete disease control. Radical resection and adjuvant treatment achieved complete disease control at 5-year follow-up in a 7-year-old girl with a lumbar intraneural synovial sarcoma.
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