Key result
POSSUM scoring accurately predicts morbidity but substantially overestimates mortality in emergency laparotomy.
Why the study?
A uniform scoring system is needed to assess morbidity and mortality risk in patients with peritonitis undergoing emergency laparotomy, especially in resource-limited settings.
Do the POSSUM and p-POSSUM scoring systems accurately predict morbidity and mortality in patients undergoing emergency laparotomy for non-traumatic peritonitis?
Cohort (n=150)
No
Do the POSSUM and p-POSSUM scoring systems accurately predict morbidity and mortality in patients undergoing emergency laparotomy for non-traumatic peritonitis?
POSSUM is a good predictor of morbidity, while p-POSSUM is better suited for predicting mortality in patients undergoing emergency laparotomy for peritonitis.
BACKGROUND is a life-threatening condition; a uniform scoring system is a must to judge the efficacy in hospital care. It aids in patients at high risk who require intensive management and also to provide a reliable objective classification of severity operative risk. With 12 clinical and basic biochemical parameters and 6 operative parameters as the basis, POSSUM is the system, which has proven ability to assess morbidity and mortality risk, especially in the health care center where only investigations are available. Application of POSSUM in developing countries with different population and limited resources done. In the present prospective study, POSSUM and p-POSSUM scoring systems applied to determine how they performed predicting complication or death in patients undergoing emergency laparotomy. total of 150 cases diagnosed to be peritonitis who underwent laparotomy at a tertiary care centre were enrolled. The for calculating POSSUM score were retrieved and O:E Ratio for Mortality and Morbidity calculated using linear and analysis. Data was entered using EPIDATA software and statistical analysis was performed using SPSS 25.0. Linear Analysis, Mean Morbidity Risk calculated by POSSUM was 73.3%. Expected and observed morbidity was 110 and 102, with O:E Ratio 0.92 (א2 - not significant) showing POSSUM morbidity equation as a good predictor of morbidity in cases peritonitis. Mean Mortality Risk as calculated by POSSUM was 32.39%. Expected and observed mortality was 49 and 21, with :E Ratio 0.43 (א2 – significant) showing POSSUM Mortality equation over predicts Mortality in cases of peritonitis especially low risk patients. Mortality risk prediction by p-POSSUM by linear analysis was 19.47%. Expected and observed mortality was 30 and 21, with O:E Ratio 0.72 (א2 - non significant). Using exponential analysis POSSUM Morbidity equation could predict accurately for risk strata 51-100 where O:E Ratio 0.99 (ℵ 2 - not significant), but א2 showed significant difference risk strata 21-40 showing that POSSUM Morbidity equation over predicts morbidity especially in low risk group. Using analysis POSSUM and p-POSSUM Mortality equations could better predict mortality with O: E Ratio. 1.04 (א2 significant) and 1.05 (א2 - not significant) respectively. SCORING SYSTEM is a good predictor of morbidity using linear analysis whereas using exponential analysis it over morbidity in low risk group (<60). POSSUM SCORE over predicts mortality using linear analysis, while the results are better when exponential analysis is used. Whereas mortality risk prediction by p-POSSUM score is better compared POSSUM score by linear and exponential analysis.
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S et al. (2019) conducted a cohort in Non-traumatic peritonitis requiring emergency laparotomy (n=150). POSSUM and p-POSSUM scoring systems was evaluated on Morbidity and mortality risk prediction (O:E Ratio 0.92 (morbidity, linear analysis), p=not significant). The POSSUM scoring system was a good predictor of morbidity (O:E ratio 0.92) but overpredicted mortality (O:E ratio 0.43) using linear analysis in patients undergoing emergency laparotomy.
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