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Many studies have shown that antihistamines and decongestants are of little use in the treatment of acute otitis media and otitis media with effusion, or in the prophylaxis of these disorders. However, because some drugs can improve otitis media with effusion (glycocorticosteroids) and some can impair the opening function of the eustachian tube (atropine), it seems justified to continue studies of eustachian tube function and medication.
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Malm et al. (1998) studied this question.
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