Key result
Obesity links to cardiovascular disease and type 2 diabetes via chronic inflammation.
Why the study?
Obesity is characterized by excessive fat accumulation and chronic inflammation, which links it to comorbidities including cardiovascular diseases.
This paper reviews the molecular basis of chronic inflammation in obesity and its link to comorbidities such as cardiovascular disease and type 2 diabetes.
Obesity-linked chronic inflammation may drive comorbidities; leaves open whether targeting redox or inflammatory pathways improves outcomes.
Almost two thousand millions of adults suffer from overweight or obesity in the world [1]. After decades of research, understand that the solution to this problem is not easy, as pernicious trend is still increasing. disease is defined as an excessive fat accumulation with a moderate but chronic inflammation. accompanying proinflammatory status is considered link between obesity and the development of its related such as insulin resistance and type 2 diabetes, diseases, cancer, and nonalcoholic fatty liver .
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Crujeiras et al. (2019) conducted a review in Obesity. Obesity is characterized by excessive fat accumulation and chronic inflammation, which serves as the link to related comorbidities like cardiovascular disease and type 2 diabetes.
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