Comparison of a New Halloysite Based Haemostatic Gauze (SpeedM) With a Kaolin Based Gauze (QuikClot Combat Gauze) in a Standardised Lethal Porcine Model of Uncontrolled Haemorrhage

Introduction: The study investigates the effectiveness of a newly developed halloysite coated haemostatic gauze (haemostatic gauze (HG), SpeedM) compared with kaolin coated QuikClot Combat Gauze (CG) in a standardised lethal porcine model of arterial haemorrhage. The study aimed to evaluate halloysite's potential as a novel haemostatic agent for traumatic bleeding treatment. Method: = 11). After a five minute compression at 200 mmHg, haemostatic performance was assessed based on primary haemostasis, need for secondary application, haemodynamic stability, and survival over a sixty minute observation period after returning to baseline. One death occurred in each group before a mean arterial pressure ≥60 mmHg was reached. The other two of the three CG fatalities occurred at a mean arterial pressure >60 mmHg. Conclusion: = 1.0), the unique physicochemical properties of halloysite may warrant further investigation in future adequately powered studies.