Thiophene appended rhodaminehydrazone derivative, RDHDTCA allows selective colorimetric and fluorescence recognition of Cu(2+) as low as 2.4 × 10(-8) M. RDHDTCA is capable to detect intracellular Cu(2+) in human breast cancer cells, MCF7 under fluorescence microscope.
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Adhikari et al. (2014) studied this question.
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