, PPi) is involved in energy transduc-tion and metabolic processes within cells. For example, the concomitant release of PPi is indispensable to intracellular enzymatic reactions such as DNA polymerization catalyzed by DNA polymerase and the synthesis of cyclic adenosine mono-phosphate (cAMP), a second messenger used for signal trans-duction in many different organisms, catalyzed by adenylyl cyclase.
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Kim et al. (2010) studied this question.
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