Key result
Fatal primary pleural angiosarcoma can present as spontaneous bilateral hemothorax without macroscopic pleural lesions.
Why the study?
Primary pleural angiosarcoma is a rare malignancy with limited clinical descriptions, especially presenting as spontaneous bilateral hemothorax without detectable masses.
Case Report (n=35)
Primary pleural angiosarcoma is a rare malignancy that can present as spontaneous bilateral hemothorax without visible masses on imaging, making antemortem diagnosis challenging.
Answers are grounded in this paper and cite their sources.
Consider angiosarcoma in unexplained bilateral hemothorax; case reports leave open needs for better antemortem diagnostics.
Angiosarcoma is a rare malignancy of vascular origin, mostly originating from skin, soft tissues, and breast, but rarely also from the pleura. We present the case of a 55-year-old man who referred to our hospital for a spontaneous bilateral hemothorax. The CT angiography did not show any source of active bleeding; plus, no pleural or lung masses were observable. Cytological and microbiological analyses made on a sample of pleural fluid resulted negative. Despite numerous blood transfusions and thoracenteses, the patient deceased from hemorrhagic shock ten days later and the diagnosis of primary pleural epithelioid angiosarcoma was obtained only by autopsy. Additionally, we present a review of the literature about primary pleural angiosarcomas.
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Levi et al. (2021) conducted a case report in Primary pleural angiosarcoma (n=35). Primary pleural angiosarcoma was evaluated. Primary pleural angiosarcoma is a rare, aggressive malignancy that can present deviously as spontaneous bilateral hemothorax without macroscopic pleural lesions, often resulting in a very poor prognosis.
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