The cutaneous manifestations of the Klippel-Trenaunay-Weber syndrome

The Klippel-Trenaunay-Weber syndrome (KTWS) is the widely accepted eponym for the condition of angioosteohypertrophy. The clinical features of limb overgrowth and various vascular malformations have been previously well-described, but the spectrum of dermatological manifestations of the KTWS is less well-documented. For this reason we have evaluated the natural history of the cutaneous lesions in 20 affected individuals. It has emerged that the hitherto unreported problem of aseptic cellulilis is a frequent and potentially severe complication in the KTWS.