Recurrent and Metastatic Trichilemmal Carcinoma of the Skin Over the Thigh: A Case Report

I n t r o d u c t i o nTrichilemmal carcinoma (TC) is a rare malignant tumor that develops from the external root sheath of the hair follicle.It usually is found in the skin of the face or ears of elderly women on areas that are exposed to the sun, and TC generally has an indolent clinical course (1,2).This condition is usually curable after a wide excision (2).TC must be differentiated from other skin abnormalities such as squamous cell carcinoma, basal cell carcinoma, keratoacanthoma, and invasive Bowen's disease (3-5).TC is a low-grade carcinoma with a low metastatic potential (6).Surgical excision is considered to be the first choice for curative treatment (7,8), and no other reliable treatment strategies for TC have yet been established (9).We report here on a case of metastatic TC involving the skin over the thigh and this was treated with cisplatin and cyclophosphamide combination chemotherapy.