The interaction of beta-amyloid (Abeta) peptides with externally applied electric fields (EF) of varying strengths was investigated by means of molecular dynamics (MD) simulations. The results suggest that the EF favors the switch of Abeta-peptides from helical to beta-sheet conformation, and a mechanism is tentatively proposed. Switching off the field does not restore the original conformation.
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Toschi et al. (2008) studied this question.
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