Key result
Gothic aortic arch after coarctation repair is linked to early vascular stiffness and systemic hypertension.
Why the study?
After successful repair of aortic coarctation, many patients remain at risk for cardiovascular problems including persistent systemic arterial hypertension with multiple pathogenic mechanisms identified.
Answers are grounded in this paper and cite their sources.
Patients with successfully repaired aortic coarctation remain at risk for systemic arterial hypertension due to various pathogenic mechanisms including residual arch stenosis and increased aortic stiffness.
After successful repair of aortic coarctation (AoCo), many patients remain at risk for cardiovascular problems and major adverse prognostic factors have been identified 1-4 .After AoCo repair, different pathogenic mechanisms leading to persistent systemic arterial hypertension have been identified, including mild residual arch stenosis, increased aortic wall stiffness, hyperactivity of reninangiotensin system, impairment of the baroreflex system and peripheral vascular reactivity 4 .
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R Crepaz (2018) conducted a review in Aortic coarctation and systemic arterial hypertension. Gothic aortic arch shape vs. Normal or crenel aortic arch shape was evaluated. Patients with a gothic aortic arch shape after successful aortic coarctation repair have an increased risk of developing early vascular stiffness and systemic arterial hypertension.
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