Key result
Infant Kawasaki disease often presents atypically and carries a ~25% untreated risk of CAA.
Why the study?
Infants younger than 6 months with Kawasaki disease often have atypical presentations and are at highest risk for coronary artery aneurysms, requiring careful identification.
Providers in acute care settings must maintain a high index of suspicion for Kawasaki disease, particularly in infants under 6 months who often present atypically, to prevent coronary artery aneurysms.
May support heightened suspicion for atypical Kawasaki disease in young infants; leaves open validation of age-specific diagnostic criteria.
Kawasaki disease (KD) is an acute vasculitis that primarily affects young children and, if untreated, is associated with development of coronary artery aneurysms in approximately 25% of those affected. Infants, especially those younger than 6 months, often have atypical (incomplete) presentations of KD and are most at risk for development of aneurysms. Identification of KD requires a careful and thorough history and physical examination because multiple other conditions cause similar findings. Providers in acute care settings need to have a high degree of suspicion for KD so that those affected may receive appropriate and timely treatment.
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Martha G. Fuller (2019) conducted a review in Kawasaki disease. Kawasaki disease in infants, particularly those under 6 months, often presents atypically and carries a high risk of coronary artery aneurysms (approximately 25% if untreated), requiring high clinical suspicion.
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