The common VWF single nucleotide variants c.2365A>G and c.2385T>C modify VWF biosynthesis and clearance

This is the authors' abstract. We don't add key points for this paper.

Key Points VWF variants c.2365A>G and c.2385T>C independently influence VWF biosynthesis and clearance, increasing VWF plasma levels. Commonly inherited VWF variants can directly influence the protein and may contribute to hemostatic and thrombotic disease risk/severity.