Liquid core capillary-based Raman probe for surface-enhanced Raman scattering detection

High-sensitivity surface-enhanced Raman scattering (SERS) signal detection was achieved using a novel optical probe based on a processed capillary tube. The probe was produced by immobilizing silver nanoparticles (SNPs) in alkanethiol self-assembled monolayers on a capillary tube wall surface through a chemical coating technique. The developed probe could detect Rhodamine 6G with good sensitivity (10 −9 ) due to enhanced interaction volume, high excitation and collection efficiency, and additional enhancement of hot nanojunctions. The proposed Raman probe provides a simple, cheap, fast, compact, and high-sensitivity SERS signal detection method for many potential applications, including chemical, biological, medical, and environmental fields.