Key result
New St-Valerien-like virus strain found in ~3% of Japanese swine feces enables virus-like particle production.
Why the study?
A novel calicivirus, St-Valerien-like virus (SVV), had been identified in asymptomatic swine in several countries, but characterization of SVV strains in Japan was lacking.
Cross-Sectional (n=76)
The detection and characterization of the NUP-24/JP strain in Japan suggests that St-Valerien-like virus is prevalent in swine worldwide.
Extends St-Valerien-like virus detection to Japanese swine; leaves open global prevalence, zoonotic risk, and surveillance needs.
A novel calicivirus, St-Valerien-like virus (SVV), has been identified in asymptomatic swine in Canada, Italy and the U.S.A. In this study, we characterized a new SVV strain (NUP-24/JP) detected in fecal samples of swine in Japan. The NUP-24/JP genome had 6,409 nucleotides and 2 open reading frames (ORF1 and ORF2). ORF1 and ORF2 consist of 5,940 and 453 nucleotides, respectively. Phylogenetic analysis revealed that NUP-24/JP was closely related to other SVV strains, particularly to U.S.A. strain NC-WGS93C/US. This finding suggests that SVV is prevalent in swine worldwide. Using a baculovirus expression system, we successfully produced virus-like particles, which would be useful for seroepidemiological studies of SVV.
No takes yet. Share an insight, caveat, or question.
Sato et al. (2014) conducted a cross-sectional in St-Valerien-like virus (SVV) infection (n=76). St-Valerien-like virus (SVV) detection was evaluated on Detection of SVV genome. A new St-Valerien-like virus strain (NUP-24/JP) was detected in 2.6% (2/76) of swine fecal samples in Japan, and its genome was characterized and used to produce virus-like particles.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: