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Background Magnetic resonance imaging T1‐weighted basal ganglia hyperintensity is observed in patients with anti‐leucine‐rich glioma‐inactivated 1 encephalitis presenting with faciobrachial dystonic seizure (FBDS), but not in patients without FBDS. Case presentation We report two patients with anti‐leucine‐rich glioma‐inactivated 1 encephalitis who developed ‘infarct‐like’ basal ganglia magnetic resonance imaging changes: one did not have FBDS, whereas the other developed FBDS 2 months after initial presentation. The lack of FBDS and unilateral basal ganglia restricted diffusion without T1‐hyperintensity resulted in the initial misdiagnosis of ischemic stroke in both cases. Conclusion Our report adds to the heterogeneity of anti‐leucine‐rich glioma‐inactivated 1 encephalitis and highlights the need to consider this diagnosis in patients who present atypically.
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Poh et al. (2021) studied this question.
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