Key result
Higher BMI categories show no association with time to in-hospital VTE among obese patients.
Why the study?
No consensus exists for optimal VTE prophylaxis in obese patients, and time to development of in-hospital VTE is not well studied.
Does BMI category impact the time to in-hospital VTE in obese patients?
Observational (n=246)
No
Does BMI category impact the time to in-hospital VTE in obese patients?
BMI category does not significantly impact the time to in-hospital VTE among obese patients, whereas care setting, surgical status, and prophylaxis strategy do.
Similar VTE timing across obese BMI strata does not support differential monitoring; leaves open whether care setting or prophylaxis should guide timing.
Background: Currently, no consensus approach exists for optimal venous thromboembolism (VTE) prophylaxis in obese (BMI ≥30 kg/m 2 ) patients. Time to development of in-hospital VTE is not well studied. Objective: This study evaluates time to in-hospital VTE in obese patients. Methods: A single-center, retrospective study evaluated obese patients that developed an in-hospital VTE. Patients were categorized into 3 BMI groups: 30 to 34.9 (group 1), 35 to 39.9 (group 2), and ≥40 (group 3) kg/m 2 . The primary end point compared time to VTE between the groups. Results: A total of 246 patients were included, and time to VTE was similar between the groups, 8 (group 1) versus 8 (group 2) versus 9 days (group 3); P = .38. Secondary outcomes showed time to VTE was shorter in acute care versus ICU patients (7.5 vs 10 days; P = .01), nonsurgical versus surgical patients (6 vs 9 days; P = .004), and no prophylaxis versus mechanical plus pharmacologic prophylaxis (4.5 vs 9 days; P < .001). Conclusions: BMI category did not significantly impact time to in-hospital VTE. This study provides insight into the timing of in-hospital VTE in obese patients. The differences in prophylactic strategies highlight the importance of optimized prophylaxis.
No takes yet. Share an insight, caveat, or question.
Cutshall et al. (2019) conducted an observational in In-hospital venous thromboembolism in obese patients (n=246). BMI category vs. Other BMI categories was evaluated on Time to VTE between the groups (p=.38). BMI category did not significantly impact time to in-hospital VTE among obese patients (8 vs 8 vs 9 days for BMI 30-34.9, 35-39.9, and ≥40 kg/m2; P=0.38).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: