We read with great interest the recent guidelines from the European Association for the Study of Liver (EASL) for the management of chronic hepatitis B [1], which were eagerly anticipated. We think that they definitely represent a step forward in the right direction for the management of chronic hepatitis B, which is a rapidly evolving field. However, we would like to draw your attention on the indications for liver biopsy, which remain a controversial unresolved issue, at least in our opinion.
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Papatheodoridis et al. (2009) studied this question.
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