The parenteral injection of a small amount of cadmium salts produces massive haemorrhagic necrosis of the gonad in male rats (Pařízek & Záhoř, 1956; Pařízek, 1960) and an analogous destruction of the foetal part of placentae in pregant female rats (Pařízek, 1964). However, no changes similar to the complete destruction of these organs were detected in the ovaries of adult female rats injected subcutaneously with the same or even a higher dose of cadmium salts (Pařízek & Záhoř, 1956; Gunn, Gould & Anderson, 1963; Maekawa, Tsunenari & Yoshitoshi, 1967). In contrast with the sterilizing effect of cadmium in the male, analogous subcutaneous injections of cadmium into female rats (before admission of the male) did not affect fertility (Pařízek, 1957a, 1960). However,
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Parízek et al. (1968) studied this question.
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