Key result
Althesin prevents age-related recovery delays, saving older patients ~17 minutes compared to thiopentone.
Why the study?
The effect of age on recovery times after induction of anaesthesia with Althesin or thiopentone in patients undergoing dilatation and curettage was unclear.
Does Althesin compared to thiopentone improve recovery time in patients undergoing dilatation and curettage across different age groups?
Comparison
Induction with Althesin vs induction with thiopentone prior to maintenance anaesthesia
Design
Randomized controlled trial
Authors
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Supports Althesin for consistent recovery across ages in D&C; extends RCT evidence favoring age-independent induction agents.
RCT (n=80)
randomly allocated
Does Althesin compared to thiopentone improve recovery time in patients undergoing dilatation and curettage across different age groups?
Althesin provides more consistent recovery times across age groups compared to thiopentone for induction of anesthesia.
Sear et al. (1983) conducted an RCT in undergoing dilatation and curettage (n=80). Althesin vs. thiopentone was evaluated on Recovery time assessed by opening eyes, giving correct date of birth, and achieving baseline manipulative skill with a post box toy. Induction of anaesthesia with Althesin resulted in no age-related difference in recovery time, whereas thiopentone increased recovery time in older patients from 28.5 to 45.1 minutes.
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