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July 17, 2023Toxicology ResearchOpen Access

Study on the mechanism of PM2.5 affecting Th1/Th2 immune imbalance through the notch signaling pathway in asthmatic mice

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JWJi-rong WuZHZheng HeHBHairong Bao

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Wu et al. (2023) studied this question.

synapsesocial.com/papers/6aacd892f974764d8f0cf459https://doi.org/10.1093/toxres/tfad044
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Role for Cysteinyl Leukotrienes in Airway Remodeling in a Mouse Asthma Model2002 · 419 citations
  2. 2Notch Ligand DLL4 Alleviates Allergic Airway Inflammation via Induction of a Homeostatic Regulatory Pathway2017 · 30 citations
  3. 3PM2.5 exposure and cold stress exacerbates asthma in mice by increasing histone acetylation in IL-4 gene promoter in CD4+ T cells2019 · 42 citations
  4. 4An improved murine model of asthma: selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolised allergen1998 · 333 citations