Key result
Older age shows no difference in Valsalva or pulse amplitude ratios versus younger healthy males.
Why the study?
The effect of aging alone, without risk factors, on autonomic nervous system function measured by Valsalva ratio and arterial pulse amplitude ratio was unclear.
Does aging without risk factors affect the autonomic nervous system as measured by Valsalva ratio and arterial pulse amplitude ratio in healthy males?
Case-Control (n=40)
No
Does aging without risk factors affect the autonomic nervous system as measured by Valsalva ratio and arterial pulse amplitude ratio in healthy males?
Aging alone, in the absence of cardiovascular risk factors, does not significantly alter autonomic nervous system function as measured by Valsalva and pulse amplitude ratios in healthy males.
Answers are grounded in this paper and cite their sources.
Provides age-stratified Valsalva ratio norms in healthy males; leaves open aging's isolated effect on autonomic function.
Aims: To construct normal values of Valsalva ratio for heart rate responses during Valsalva maneuver (VM) and arterial pulse amplitude ratio as reference values for different age groups, and to investigate the effect of aging alone , without , the presence of risk factors, on autonomic nervous system.This is a case control study, performed in Marjan teaching hospital, in Hilla city, from February 2012 to June 2012.Methodology: 40 subjects were included in this study, all were healthy males, group 1 (G1) mean age 28.3±9.7 years, group 2 (G2) mean age 48.4±7.1 years.Strips of lead II of ECG were recorded during performance of VM for calculation R-R intervals and measurement of blood pressure during phase I and phase II by mercury sphygmomanometer.Calculation of Valsalva ratio for heart rate and arterial pulse amplitude ratio for both groups were done.Results: The systolic and diastolic blood pressures of G2 were significantly higher than values of systolic and diastolic blood pressures of G1 at phase I and phase II of VM Short Research Article(P=0.05).Pulse pressure for the two groups at phase I (G1:51±11, G2: 53±13mmHg) and phase II (G1:41±5, G2:41±3.99) of VM were not significant (P>0.05).Valsalva ratio for G1 was (1.5±0.3) and for G2 was (1.39±0.29),pulse amplitude ratio for G1 was (0.80±0.19) and for G2 was (0.77±0.19).There were no significant differences between the two groups (P>0.05).All values were expressed as mean±SD. Conclusions:The results showed that the autonomic nervous system is intact in the older group.The aging process, without the presence of risk factors, does not affect the autonomic nervous system.
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Y. M. H. Al-Shamma (2014) conducted a case-control in Healthy (n=40). Older age vs. Younger age was evaluated on Valsalva ratio (p=>0.05). Older age without risk factors did not significantly affect the Valsalva ratio (1.39 vs 1.50) or pulse amplitude ratio (0.77 vs 0.80) compared to younger age in healthy males (P>0.05).
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