The origin and development of osmiophilic inclusion bodies (OIB) type A of granular pneumocytes were morphologically studied in chicken lungs. The OIB type A were formed by a process of twisting and progressive spiraling of profiles of the rough endoplasmic reticulum (RER). No evidence has been found in favor of a mitochondrial or Golgi-related origin of OIB.
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López et al. (1984) studied this question.
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