Key result
CAT score >20 linked to ~688% higher odds of major depression in stable COPD patients.
Why the study?
Depression is a common comorbidity among COPD patients and impacts disease course, but its association with CAT score in mild hypoxemia is unclear.
Is a CAT score >20 associated with major depression in clinically stable out-patient COPD subjects with mild hypoxemia?
Comparison
CAT score >20 vs lower CAT scores
Design
Case-control study
Authors
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CAT >20 flags depression risk in stable COPD; leaves open prospective validation before screening use.
Case-Control (n=60)
No
Is a CAT score >20 associated with major depression in clinically stable out-patient COPD subjects with mild hypoxemia?
Odds Ratio: 7.88 (95% CI 1.96–31.7)
p-value: p=0.004
A CAT score >20 is a strong predictor of major depression in COPD patients with mild hypoxemia, suggesting it could be used to screen for depression in this population.
Júnior et al. (2014) conducted a case-control in Chronic Obstructive Pulmonary Disease (COPD) with mild hypoxemia (n=60). COPD Assessment Test (CAT) score >20 vs. CAT score ≤20 was evaluated on Major depression diagnosed according to DSM IV criteria (OR 7.88, 95% CI 1.96 - 31.7, p=0.004). A COPD Assessment Test (CAT) score >20 was significantly associated with major depression (OR 7.88) among clinically stable COPD patients with mild hypoxemia.
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