Changes in serous and encephalic serotonin in hypophysectomized or adrenalectomized rats have been observed. Adrenalectomy produces a decrease of serous serotonin and an increase of the serotonin of hemispheres, base, and medulla oblongata; with hypophysectomy, serotonin is also reduced in serum and increased only in the base and medulla oblongata.
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D. De Maio (1959) studied this question.
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