Why the study?
Morin's broad neuroprotective, anti-inflammatory, and antioxidant effects across diverse neurodegenerative and neurotoxic models require consolidation to evaluate its consistent benefits and mechanisms.
Does morin improve survival, motor/cognitive performance, and biochemical normalization in in vitro and rodent models of neurotoxicity and neurodegeneration?
Population
In vitro and rodent models of neurodegenerative proteinopathies, neuropathic pain, epilepsy, stress- and schizophrenia-like phenotypes, and neurotoxicity
Comparison
Morin exposure vs no morin or control conditions
Design
Review of preclinical in vitro and rodent studies
Key result
Morin emerges as a multitarget neuroprotective scaffold with reproducible functional and mechanistic benefits across in vitro and rodent models of neurodegeneration and neurotoxicity.
Authors
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Morin shows consistent preclinical neuroprotection; leaves open clinical translation and requires human trials before any therapeutic consideration.
Does morin improve survival, motor/cognitive performance, and biochemical normalization in in vitro and rodent models of neurotoxicity and neurodegeneration?
Morin is a multitarget neuroprotective scaffold with reproducible functional and mechanistic benefits in preclinical models, warranting further translational research.
Ekundayo et al. (2026) conducted a review in Neurotoxicities and Neurodegenerative Diseases. Morin was evaluated. Morin emerges as a multitarget neuroprotective scaffold with reproducible functional and mechanistic benefits across in vitro and rodent models of neurodegeneration and neurotoxicity.
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