Serial [5+2]/[4+2] Cycloadditions: Facile, Preparative, Multi‐Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials

Four new bonds and up to four new stereocenters are formed in the title reactions which allow the conversion of readily available starting materials into complex bicyclo[5.4.0]undecane derivatives (see scheme). The reactions are performed in a single, simple operation that can be conducted on a preparative scale (100 mmol thus far).