Why the study?
The relationship between myocardial fibrosis assessed non-invasively and left ventricular longitudinal systolic function in essential hypertension was unclear.
Is myocardial fibrosis assessed by plasma PIIINP related to left ventricular longitudinal systolic function in patients with essential hypertension?
Observational (n=70)
Is myocardial fibrosis assessed by plasma PIIINP related to left ventricular longitudinal systolic function in patients with essential hypertension?
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In patients with essential hypertension, increased myocardial fibrosis (indicated by elevated PIIINP) is significantly associated with reduced left ventricular longitudinal contractility.
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Juarez Neuhaus Barbisan (2005) conducted an observational in Essential hypertension (n=70). Essential hypertension vs. Control subjects was evaluated on Mean left ventricular longitudinal systolic strain (p=<0.01).
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