Key result
Liver transplantation outcomes and post-operative complications are detailed in patients with familial hypercholesterolemia.
Why the study?
Familial hypercholesterolemia causes premature atherosclerosis and myocardial infarction, and liver transplantation is the most effective therapy in refractory cases.
What are the clinical outcomes and complications of liver transplantation in patients with familial hypercholesterolemia?
Case Report (n=36)
No
What are the clinical outcomes and complications of liver transplantation in patients with familial hypercholesterolemia?
Liver transplantation is presented as a definitive treatment for refractive cases of familial hypercholesterolemia in a series of 36 patients.
May support consideration in refractory cases; leaves open need for prospective trials on safety and efficacy.
FH is a genetic disorder characterized by an increase in serum LDL and total cholesterol values. The afflicted patients are at increased risk of premature atherosclerosis and myocardial infarction. Different treatment modalities are present, including pharmacological agents and surgical procedures. The most effective method of therapy in refractive cases is liver transplantation. Herein, we report our experience on 36 cases of patients with FH undergoing liver transplantation in our center, the main referral center of liver transplantation in Iran. The clinical findings, hospital courses, post-operative complications, and patient follow-up are also described.
No takes yet. Share an insight, caveat, or question.
Mansoorian et al. (2015) conducted a case report in Familial hypercholesterolemia (n=36). Liver transplantation was evaluated.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: