Triazoles as complexing agents: synthesis, characterization and pharmacological activities of copper complexes of 4-amino-3-mercapto-5-substituted aryl-1,2,4-triazoles

Copper complexes of 4-amino-3-mercapto-5-substituted aryl-1,2,4-triazoles 2(a–j) have been prepared in the ethanolic medium and characterized by elemental analysis, IR, TGA, 1H NMR and magnetic susceptibility studies. The ligand is bidentate with SN donors of the mercapto S and amino N. Some compounds show significant anti-inflammatory and analgesic activities.