Summary A patient with a reticulum cell sarcoma and cold agglutinin of the IgA type is reported. The cold agglutinin had a sedimentation rate of 10.5S (9.5–11.5S), indicating that it is probably a dimer of the 7-8S IgA unit. The cold agglutinin was mercaptoethanol sensitive and failed to fix complement.
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Angevine et al. (1966) studied this question.