Key result
Ethnicity was not significantly associated with postoperative nausea and vomiting (34.6% Chinese vs 34.2% Malay vs 29.4% Indian, p=0.695), though young Indian females had a higher risk (p=0.02).
Why the study?
The influence of ethnicity on the risk of postoperative nausea and vomiting (PONV) and the correlation of known risk factors in Singapore's multiethnic population were unclear.
Does ethnicity affect the risk of postoperative nausea and vomiting in patients undergoing elective orthopaedic surgery?
Observational (n=785)
No
Does ethnicity affect the risk of postoperative nausea and vomiting in patients undergoing elective orthopaedic surgery?
Ethnicity is generally not a significant risk factor for postoperative nausea and vomiting in this multiethnic population, though young Indian females may have a higher risk of postoperative vomiting.
Ethnicity need not modify PONV prophylaxis in orthopaedic surgery; hypothesis-generating for elevated risk in young Indian females.
Introduction. We explored how ethnicity affects the risk of postoperative nausea and vomiting (PONV) and established the correlation of suggested risk factors of PONV in the multiethnic population of Singapore. Methods. 785 patients who underwent orthopaedic surgery were recruited. These comprised 619 Chinese (78.9%), 76 Malay (9.7%), 68 Indian (8.7%), and 22 other (2.8%) cases. The presence of possible risk factors of PONV and nausea and/or vomiting within 24 h after surgery was studied. Univariate and multivariate logistic regression analyses were performed. Results. The incidence of PONV was 33.2% (261 patients). There was no statistically significant difference of PONV incidence between Chinese, Malay, and Indian cases (34.6% versus 34.2% versus 29.4%, p=0.695 ). Indian females younger than 50 years were found to have a higher incidence of vomiting ( p=0.02 ). The significant risk factors for this population include females, use of nitrous oxide, and a history of PONV. Conclusion. In the groups studied, ethnicity is not a significant risk factor for PONV except for young Indian females who have a higher risk of postoperative vomiting. We suggest the selective usage of antiemetic for young Indian females as prophylaxis and avoiding nitrous oxide use in high-risk patients.
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Leong et al. (2015) conducted an observational in Postoperative nausea and vomiting (n=785). Ethnicity vs. Compared among Chinese, Malay, and Indian patients was evaluated on Incidence of postoperative nausea and vomiting within 24 h after surgery (p=0.695). Ethnicity was not significantly associated with postoperative nausea and vomiting (34.6% Chinese vs 34.2% Malay vs 29.4% Indian, p=0.695), though young Indian females had a higher risk (p=0.02).
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