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Five new naturally occurring anthracene derivatives, 1,4,10-trimethoxyanthracene-2-carbaldehyde (1), (1,4,10-trimethoxy-2-anthracen-2-yl)methanol (2), 1,4,8,10-tetramethoxyanthracene-2-carbaldehyde (3), 1,4,10-trimethoxyanthracene-2-carboxylic acid (4), and 1,3-dimethoxy-2-methoxymethylanthraquinone (5), were isolated from Coussarea macrophylla along with three known compounds, 3-hydroxy-1-methoxy-2-methoxymethylanthraquinone (6), scopoletin, and 3-epi-pomolic acid. The structures of 1-5 were determined on the basis of analysis of their spectroscopic data and by total synthesis.
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Chiriboga et al. (2003) studied this question.
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