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During 2021 and 2022, the pandemic of corona viruses (COVID-19) caused the enormous increase in use of antioxidants and supplements. The latest recommendations from the World Health Organization were to use natural sources of antioxidants which can help in boosting immunity (WHO, 2019). Dietary antioxidants from fruits and vegetables play an important role in mitigating the damaging effects of reactive oxygen species (ROS) on cellular macromolecules (lipids, proteins, and DNA) (Rao et al., 2010). The raspberries have high antioxidant phytochemical contents which can be preserved by freezedried process. The yield of bioactive compounds from plant sources depends on solvent properties, nature of the plant material and extraction temperature and time (Xue et al., 2020). In the green chemistry approaches, natural deep eutectic solvents (NADES) were typically used as a substitute for organic solvents in order to preserve the environment (Espino et al., 2016).
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Ljujić et al. (2022) studied this question.
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