A Flexible, Stereoselective Approach to the Decorated cis‐Hydrindane Skeleton: Synthesis of the Proposed Structure of Faurinone

This is the authors' abstract. We don't add key points for this paper.

Two electrons, three new stereocentres: The cis-hydrindane motif is found in a number of natural products that display important biological activity. A flexible, stereoselective approach to the framework has been developed that features highly diastereoselective, SmI2-mediated cyclisations. The strategy has been exploited in the first synthesis of the proposed structure of faurinone, a sesquiterpene ketone isolated from Valeriana officinalis.