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February 1, 1978Biochemical JournalOpen Access

Preferential nitration with tetranitromethane of a specific tyrosine residue in penicillinase from Staphylococcus aureus PCl. Evidence that the preferentially nitrated residue is not part of the active site but that loss of activity is due to intermolecular cross-linking

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Authors

ABAdrian F. BristowNational Institute for Biological Standards and ControlRVRichard VirdenUniversidad Complutense de Madrid

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Bristow et al. (1978) studied this question.

synapsesocial.com/papers/6aadd6089ac3f076ca873cf3https://doi.org/10.1042/bj1690381
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Environmentally Sensitive Tyrosyl Residues. Nitration with Tetranitromethane*1967 · 192 citations
  2. 2Sequence Analysis of Fluorescamine‐Stained Peptides and Proteins Purified on a Nanomole Scale1974 · 147 citations
  3. 3The cross-linking of tyrosine by treatment with tetranitromethane1971 · 55 citations