Key result
Age 65 and older correlates with higher CHD and dyslipidemia prevalence in T2D patients.
Why the study?
Age and gender disparities in the occurrence and treatment of dyslipidemia and coronary heart disease in patients with type 2 diabetes mellitus were previously reported but not well characterized in Romanian patients.
Cross-Sectional (n=217)
No
Despite higher statin prescription rates in older patients, a significant proportion of Romanian T2DM patients with CHD or dyslipidemia remain undertreated.
Highlights persistent undertreatment of CHD and dyslipidemia in older Romanian T2DM patients; leaves open whether age-specific strategies improve outcomes.
Previous studies have reported age and gender disparities in the occurrence and therapeutic approach of dyslipidemia and (or) coronary heart disease (CHD) in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate these differences in Romanian patients with T2DM. A cross-sectional, observational, retrospective study was conducted using the medical records of T2DM patients who attended the outpatient facility of the Internal Medicine Clinic of the Clinical Emergency Hospital of Bucharest, Romania for routine check-ups in a six-month period. We analyzed the records of 217 diabetic patients (mean age 69 ± 11 years; 51.15% women). We found no significant gender differences in the occurrence of dyslipidemia, CHD or CHD + dyslipidemia or in terms of statin prescription. However; patients aged 65 years or older were significantly more affected by dyslipidemia, CHD or CHD + dyslipidemia, versus subjects aged <65 years. Further, they were more likely to be prescribed statin therapy (p < 0.0001 for all). Statins were prescribed to 67.24% of the patients with dyslipidemia; 61.01% of the subjects with CHD; and to 91.48% of the patients who had both conditions. e recorded no gender differences in the occurrence of CHD and (or) dyslipidemia in Romanian T2DM patients. Patients aged 65 years or older had a higher prevalence of CHD and/or dyslipidemia, and were more likely to be prescribed statins, versus younger counterparts. However, many T2DM patients with CHD and (or) dyslipidemia were undertreated: Nearly 33% of the subjects with dyslipidemia, and nearly 40% of the ones with CHD were not prescribed statins.
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Găman et al. (2020) conducted a cross-sectional in Type 2 diabetes mellitus (n=217). Age ≥ 65 years vs. Age < 65 years was evaluated on Prevalence of dyslipidemia, coronary heart disease (CHD), or both (p=<0.0001). In Romanian patients with type 2 diabetes, patients aged 65 years or older had a significantly higher prevalence of coronary heart disease and dyslipidemia compared to younger patients, while no significant gender differences were observed.
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