Summary: We describe a tool, called ACE-it (Array CGH Expression integration tool). ACE-it links the chromosomal position of the gene dosage measured by array CGH to the genes measured by the expression array. ACE-it uses this link to statistically test whether gene dosage affects RNA expression. Availability: ACE-it is freely available at Contact: b.ylstra@vumc.nl Supplementary Information: Programs, the manual and supplementary information are available on the website.
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Wieringen et al. (2006) studied this question.
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