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Introduction The advent of induced pluripotent stem cells (iPSCs) has opened up new avenues for generating human cell and tissue-specific organoids in vitro, by reprogramming adult somatic cells to an embryonic stem cell-like state for use in directed differentiation [1]. Directed differentiation of human intestinal organoids (HIO) from iPSC has been
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Kauffman et al. (2015) studied this question.
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