Key result
Delayed-to-morning lung transplantation had comparable 30-day mortality (3% vs 3%; P=.99) and 3-year survival (70% vs 77%; P=.3) compared to propensity-matched daytime procedures.
Why the study?
Does delayed-to-morning lung transplantation affect mortality and complications compared to immediate overnight transplantation?
Does delayed-to-morning lung transplantation affect mortality and complications compared to immediate overnight transplantation?
Absolute Event Rate: 3% vs 3%
p-value: p=.99
Delaying overnight lung transplantation procedures to the morning appears safe, with no significant differences in mortality or complications.
We read with great interest the article by Kim and colleagues1 that evaluated the outcomes of delayed-to-morning lung transplantation procedures that would have otherwise occurred overnight. Their single institution analysis identified 34 patients whose donor crossclamp times occurred between 1:30 AM and 5:00 AM, but who were consented to delay the recipient procedure until 6:30 AM (Night). When compared with 68 propensity score-matched patients whose organ procurement and transplant occurred at all other times (Day), they found comparable 30-day mortality (3% vs 3%; P = .99), postoperative complications (26% vs 38%; P = .28), 3-year survival (70% vs 77%; P = .3), and freedom from chronic lung allograft dysfunction (91% vs 95%; P = .75).
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Kwon et al. (2024) conducted a letter in Lung transplantation (n=102). Delayed-to-morning lung transplantation vs. Organ procurement and transplant at all other times (Day) was evaluated on 30-day mortality (p=.99). Delayed-to-morning lung transplantation had comparable 30-day mortality (3% vs 3%; P=.99) and 3-year survival (70% vs 77%; P=.3) compared to propensity-matched daytime procedures.
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