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June 1, 2021Cell ReportsOpen Access

Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation

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Authors

YSYong ShenKTKejun TangDCDongdong Chen

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Shen et al. (2021) studied this question.

synapsesocial.com/papers/6aadecd43a629674b6b324edhttps://doi.org/10.1016/j.celrep.2021.109272
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1RIOK3-Mediated Phosphorylation of MDA5 Interferes with Its Assembly and Attenuates the Innate Immune Response2015 · 78 citations
  2. 2Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I–mediated antiviral innate immunity2014 · 169 citations
  3. 3Human RioK3 is a novel component of cytoplasmic pre-40S pre-ribosomal particles2012 · 54 citations
  4. 4RNA recognition and signal transduction by RIG‐I‐like receptors2008 · 597 citations
  5. 5Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response2015 · 80 citations