Key result
Gastroscopic foreign body removal and supportive care resolve zinc toxicity-induced pericardial effusion in a dog.
Why the study?
Pericardial effusion has not been previously described in dogs with zinc toxicity.
Case Report (n=1)
This case report provides the first description of pericardial effusion occurring in a dog with zinc toxicity, which resolved following removal of the zinc source and supportive care.
Case of zinc toxicity with coagulopathy in a dog; hypothesis-generating for haemostatic management and warrants prospective data.
Zinc toxicity in dogs has been associated with gastrointestinal irritation and ulceration, haemolytic anaemia, acute liver injury, acute kidney injury and haemostatic abnormalities. In this case, a 2‐year‐old female spayed Golden Retriever presented to a private specialist hospital for anaemia with a 24–36 h history of lethargy, hyporexia, ptyalism and pigmenturia. Initial diagnostics identified a regenerative anaemia with hyperbilirubinaemia and prolonged activated partial thromboplastin clotting time. The patient was treated with a packed red blood cell transfusion and point of care ultrasound pre‐transfusion identified a small‐volume pericardial effusion. Abdominal radiographs identified a gastric metal opacity foreign object, which was removed via gastroscopy. After receiving 26 h of supportive care in hospital, the patient experienced a marked improvement and was discharged. On re‐examination 11 days later, the pericardial effusion had resolved. Pericardial effusion has not been previously described in a dog with zinc toxicity.
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Brnabic et al. (2025) conducted a case report in Zinc toxicity (n=1). Zinc toxicity was evaluated on Resolution of pericardial effusion and clinical improvement. A 2-year-old dog with zinc toxicity developed a small-volume pericardial effusion that resolved following supportive care and gastroscopic removal of a gastric metal foreign object.
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