Key result
RACHS-1 and PRISM scores show moderate and poor discrimination for 30-day pediatric cardiac surgery mortality.
Why the study?
The comparative performance of RACHS-1 and PRISM scores for operative risk prediction after paediatric open-heart surgery was unclear.
Does the RACHS-1 score or PRISM score accurately predict 30-day mortality in children undergoing congenital open-heart surgery?
Cohort (n=1,001)
No
Does the RACHS-1 score or PRISM score accurately predict 30-day mortality in children undergoing congenital open-heart surgery?
Both RACHS-1 and PRISM scores have limited discrimination and overestimate 30-day mortality in children undergoing congenital open-heart surgery.
Both scores showed limited predictive value for 30-day mortality; leaves open the need for improved risk models in pediatric congenital heart surgery.
This study compared the performance of risk adjustment for congenital heart surgery (RACHS-1) score with paediatric risk of mortality (PRISM) score in operative risk prediction after open-heart surgery in children. This was a retrospective analysis of a non-selected patient population from the paediatric intensive care unit of Helsinki University Hospital. All consecutive congenital open-heart surgery patients operated in Finland between the years 2000 and 2004, who were under 18 years of age, were included in this retrospective analysis. Predicted probability of mortality was calculated using the published algorithms for RACHS-1 and PRISM. Those were compared with observed mortality at day 30 postoperatively. Of the 1001 patients, 42 patients died (4.2%) within 30 days of open-heart surgery. The discrimination power, evaluated by AUC (area under curve) for RACHS-1 was moderate: 0.74 (95% CI 0.66-0.82). The AUC-value for PRISM was poor, namely 0.66 (95% CI 0.57-0.75). Both risk scoring systems overestimated the mortality with calculated standardised mortality ratios (SMR) of 0.48 for PRISM and 0.39 for RACHS-1. With only a moderate discriminating AUC, RACHS-1 failed to adequately predict death after paediatric open-heart surgery. The predictive power of PRISM in this patient group was poor. Both scores overestimated the actual mortality rate.
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Mildh et al. (2007) conducted a cohort in Congenital heart disease requiring open-heart surgery (n=1,001). RACHS-1 score vs. PRISM score was evaluated on Observed mortality at day 30 postoperatively. RACHS-1 (AUC 0.74, 95% CI 0.66-0.82) and PRISM (AUC 0.66, 95% CI 0.57-0.75) scores showed moderate and poor discrimination for 30-day mortality after pediatric open-heart surgery.
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