Propoxyphene hydrochloride, since its introduction in late 1957, has become a widely prescribed drug because of its presumed efficacy as an equivalent to narcotics and its low incidence of side effects. Miller [1], based on his critical review of the drug, found that dextropropoxyphene is ironically “no more effective than aspirin or codeine and may even be inferior to those analgesics” although more prescriptions for dextropropoxyphene were dispensed in this country in 1969 than for any other drug.
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Cravey et al. (1974) studied this question.
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