Key result
Low-dose bupivacaine-fentanyl significantly shortened the duration of spinal block and PACU stay (100.2 vs 145.3) with fewer hemodynamic adverse effects compared to prilocaine-fentanyl in geriatric patients undergoing TURP.
Why the study?
Many geriatric patients undergoing TURP have coexisting cardiac or pulmonary diseases, necessitating anesthetic techniques that limit block distribution to prevent hemodynamic and pulmonary adverse effects.
RCT (n=50)
No
Answers are grounded in this paper and cite their sources.
May support faster recovery in geriatric TURP; hypothesis-generating and requires randomized confirmation.
Spinal anaesthesia (SA) is the most commonly used anesthetic technique for transurethral resection of prostate (TURP) surgery in geriatric patient population[ 1 ]. Many geriatric patients have coexisting cardiac or pulmonary diseases, so it's very important to limit the distribution of the block to prevent the possible hemodynamic and pulmonary adverse effects. The purpose of this study is to compare the effectiveness of using intrathecal low dose bupivacaine-fentanyl combination with conventional dose prilocaine-fentanyl combination for day case TURP surgery in geriatric patient population[ 1 ]. We hypothesized that, using low dose bupivacaine-fentanyl combination provides shorter duration of block duration and postanesthesia care unit (PACU) stay with better hemodynamic stability than using conventional dose prilocaine-fentanyl combination.
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d’Elia et al. (2013) conducted an RCT in Transurethral resection of prostate (TURP) (n=50). Bupivacaine-fentanyl vs. 50 mg prilocaine 2% + 25 µg fentanyl was evaluated on Duration of spinal block and PACU stay. Low-dose bupivacaine-fentanyl significantly shortened the duration of spinal block and PACU stay (100.2 vs 145.3) with fewer hemodynamic adverse effects compared to prilocaine-fentanyl in geriatric patients undergoing TURP.
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